Click Vacation Message from the Local Account setting in the Mail section located under the Options tab on the left panel.
The Vacation Message tab appears in the central panel.
Check the Enable auto-reply box.
This enables your Inbox to send replies automatically to all incoming messages.
Select the start and end date from the vacation duration pane.
Each sender will receive an automated reply when the send their first message. You can set the number of hours after which an auto reply is again sent to the same sender. Enter the duration in hours in the Hours between replies field.
Enter the vacation message for both coworkers and other senders in the respective text areas.
Click Save Preferences.